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Laboratory Research

  1. Lee ME, Dyer DH, Klein OD, Bolduc JM, Stoddard BL, Koshland DE, Jr. Mutational analysis of the catalytic residues lysine 230 and tyrosine 160 in the NADP(+)-dependent isocitrate dehydrogenase from Escherichia coli. Biochemistry 1995; 34:378-84.
  2. Surti T, Klein O, Aschheim K, DiMaio D, Smith SO. Structural models of the bovine papillomavirus E5 protein. Proteins 1998; 33:601-12. Click Here to View
  3. Klein O, Polack GW, Surti T, Kegler-Ebo D, Smith SO, DiMaio D. Role of glutamine 17 of the bovine papillomavirus E5 protein in platelet-derived growth factor beta receptor activation and cell transformation. J Virol 1998; 72:8921-32. Click Here to View
  4. Klein O, Kegler-Ebo D, Su J, Smith S, DiMaio D. The bovine papillomavirus E5 protein requires a juxtamembrane negative charge for activation of the platelet-derived growth factor beta receptor and transformation of C127 cells J Virol 1999; 73:3264-72 Click Here to View
  5. Klein OD, Minowada G, Peterkova R, Kangas A, Yu BD, Lesot H, Peterka M,
    Jernvall J, Martin GR. Sprouty genes control tooth number via bidirectional antagonism of epithelial-mesenchymal FGF signaling. Dev Cell 2006; 11:181-190. Click Here to View
  6. Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M,
    Boran T, Peterkova R, Martin GR. An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development 2008; 135:377-385. Click Here to View
  7. Metzger RJ, Klein OD, Martin GR, Krasnow MA. The branching programme of mouse lung development. Nature; in press. Click Here to View

Clinical Research

  1. Raga F, Bonilla-Musoles F, Casan EM, Klein O, Bonilla F. Assessment of endometrial volume by three-dimensional ultrasound prior to embryo transfer: clues to endometrial receptivity. Hum Reprod 1999; 14:2851-4.
  2. Klein OD, Cotter PD, Albertson DG, Pinkel D, Tidyman WE, Moore MW,
    Rauen KA. Prader-Willi syndrome resulting from an unbalanced translocation: characterization by array comparative genomic hybridization. Clin Genet 2004; 65:477-82.
  3. Klein OD, Backstrand K, Cotter PD, Marco E, Sherr E, Slavotinek A. Case report: Y;6 translocation with deletion of 6p. Clin Dysmorphol 2005; 14:93-96. Click Here to View
  4. Ahn CP, Lachman RS, Cox VA, Blumberg B, Klein OD. Brachydactylic multiple delta phalanges plus syndrome. Am J Med Genet A 2005; 138:41-4. Click Here to View
  5. Klein OD, Cotter PD, Schmidt AM, Bick DP, Tidyman WE, Albertson DG,
    Pinkel D, Rauen KA. Interstitial deletion of chromosome 12q: Genotype-phenotype correlation of two patients utilizing array comparative genomic hybridization. Am J Med Genet A 2005; 138:349-54. Click Here to View
  6. Klein OD, Cotter PD, Moore MW, Zanko A, Gilats M, Epstein CJ, Conte F,
    Rauen KA. Interstitial deletions of chromosome 6q: genotype-phenotype correlation utilizing array CGH. Clin Genet 2007; 71:260–266. Click Here to View
  7. Klein OD, Kostiner DR, Weisiger K, Moffatt E, Lindeman N, Goodman S,
    Tuchman M, Packman S. Acute fatal presentation of ornithine transcarbamylase deficiency in a previously healthy male Hepatol Int; in press. Click Here to View

Review Articles and Book Chapters

  1. DiMaio D, Lai CC, Klein O. Virocrine transformation: the intersection between viral transforming proteins and cellular signal transduction pathways. Annu Rev Microbiol 1998; 52:397-421. Click Here to View
  2. Enns G, Cowan T, Klein O, Packman S. Aminoacidopathies and organic acidemias. In: Swaiman K, Ashwal S,
    Ferriero D, eds.     Pediatric Neurology: Principles and Practice. Philadelphia: Elsevier, 2006.
  3. D'Souza RD and Klein OD. Unraveling the molecular mechanisms that lead to supernumerary teeth in mice and men: current concepts and novel approaches. Cells, Tissues, Organs 2007: in press. Click Here to View