Program in Craniofacial Biology (PCB)
Program in Craniofacial Biology
The UCSF Program in Craniofacial Biology (PCB) brings together faculty, research labs and investigators, who are interested in the development and function of the craniofacial complex and of tissues of mesenchymal origin, such as muscle, cartilage, and bone. Researchers in the PCB Program also study the biology of a variety of stem cells, and how these progenitors differentiate into tissues. Finally, PCB Program researchers study interactions between tissues, such as the interactions between mesenchymal and epithelial tissues, how tissue differentiation and interactions give rise to normal craniofacial development, and how deregulation of tissue differentiation and interactions is at the basis of many craniofacial anomalies and musculoskeletal diseases.
The UCSF Craniofacial Center treats all types of conditions affecting the face, head and neck, whether they were present at birth or acquired from a trauma or tumor. The most common conditions include cleft lip, cleft palate and craniosynostosis syndromes, which involve the early fusing of one or more of the bones in the skull and face during fetal development.