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Tejal Desai Ph.D.

Micro and nanofabrication techniques

Tejal Desai Ph.D.

Our research applies microscale and nanoscale technologies to create new and improved ways to deliver medicines to target sites in the body and to enable the body to heal itself. Our work is based on the idea that if we can understand and manipulate the world at the microscale and nanoscale, we can engineer biomedical technologies that interact directly with cells, drugs, and biomolecules.

Selected publications:

Calcium phosphate nanoparticles: a future therapeutic platform for the treatment of osteomyelitis? Tejal A Desai, Vuk Uskoković Therapeutic Delivery, Vol. 4, No. 6, Pages 643-645, June 2013.

Nano- and microfabrication for overcoming drug delivery challenges. Kimberly R. Kam, Tejal A. Desai. J. Mater. Chem. B. 2013,1, 1878-1884 Epub 2013 Feb 20.

The Effect of Calcium Phosphate Particle Shape and Size on their Antibacterial and Osteogenic Activity in the Delivery of Antibiotics in vitro. Uskokovic V, Batarni S, Schweicher J, King A, Desai TA. ACS Appl Mater Interfaces. 2013 Mar 13 [Epub ahead of print]

Ocular Biocompatibility and Structural Integrity of Micro- and Nanostructured Poly(caprolactone) Films. Bernards DA, Bhisitkul RB, Wynn P, Steedman MR, Lee OT, Wong F, Thoongsuwan S, Desai TA. J Ocul Pharmacol Ther. 2013 Mar; 29(2):249-57. Epub 2013 Feb 7.

Radially Branched Deployment for More Efficient Cell Transplantation at the Scale of the Human Brain. Silvestrini MT, Yin D, Coppes VG, Mann P, Martin AJ, Larson PS, Starr PA, Gupta N, Panter SS, Desai TA, Lim DA. Stereotact Funct Neurosurg. 2013 Jan 22;91(2):92-103. [Epub ahead of print]

Nanostructure-Mediated Transport of Biologics across Epithelial Tissue: Enhancing Permeability via Nanotopography. Kam KR, Walsh LA, Bock SM, Koval M, Fischer KE, Ross RF, Desai TA. Nano Lett. 2013 Jan 9;13(1):164-71. Epub 2012 Dec 24.

Vuk Uskokovic, Tejal A. Desai – “Phase Composition Control of Calcium Phosphate Nanoparticles for Tunable Drug Delivery Kinetics and Treatment of Osteomyelitis. Part 2: Antibacterial and Osteoblastic Response”, Journal of Biomedical Materials Research Part A (in press, 2012).

Vuk Uskokovic, Tejal A. Desai – “Phase Composition Control of Calcium Phosphate Nanoparticles for Tunable Drug Delivery Kinetics and Treatment of Osteomyelitis. Part 1: Preparation and Drug Release”, Journal of Biomedical Materials Research Part A (in press, 2012).

Chavez MG, Yu W, Biehs B, Harada H, Snead ML, Lee JS, Desai TA, Klein OD. Characterization of Dental Epithelial Stem Cells from the Mouse Incisor with Two-Dimensional and Three-Dimensional Platforms. Tissue Eng Part C Methods, 2012; In Press.

Chirra HD, and Desai TA. Multi-reservoir bioadhesive microdevices for independent rate-controlled delivery of multiple drugs. Small. 2012; In Press.