Dr. Caroline H. Shiboski, Professor and Interim Chair of the Department of Orofacial Sciences, announces the appointment of Ophir Klein, MD, PhD, as Interim Chair of the Division of Orthodontics in the Department of Orofacial Sciences.
Dr. Klein is Larry L. Hillblom Distinguished Professor in Craniofacial Anomalies and Chair of the Division of Craniofacial Anomalies  in the Departments of Orofacial Sciences and Pediatrics. He is also the Director of the UCSF Program in Craniofacial and Mesenchymal Biology.
Dr. Klein attended Yale University School of Medicine, where he received a PhD in Genetics, and an MD degree. He then completed residencies at Yale-New Haven Hospital in Pediatrics, and at UCSF in Clinical Genetics.
Dr. Klein's research focuses on three main areas. The first area involves understanding the processes underlying craniofacial and dental development. His lab uses mouse models to study the mechanisms responsible for the normal and abnormal development of teeth, facial skeleton and other organs, as well as the regeneration of these organs. A second major area of investigation involves studying the function of positive and negative regulators of receptor-kinase signaling. A third focus is on the stem cells that renew the lining of the intestine, oral cavity, and other organs.
Dr. Klein has strong connections with the Division of Orthodontics, since both his research and his clinical practice closely intersect with the specialty. He has also demonstrated outstanding leadership as the Director of the Center for Craniofacial Anomalies, completing implementation of the use of the Apex system for the Center’s Electronic Health Records, and significantly strengthening ties with the UCSF Medical Center.
"Dean Featherstone and I are very grateful to Dr. Klein for accepting the appointment as Interim Chair of the Division of Orthodontics," says Dr. Shiboski, "and for taking on the additional responsibilities of leading the division until a permanent chair is appointed. Please join me in welcoming him to this new position."
Dr. Ophir Klein