University of California San Francisco
Diane Barber, PhD
Professor and Chair
The Barber lab is pioneering a molecular understanding of how intracellular pH dynamics regulates cell behaviors. We bridge protein electrostatics and cell biology to reveal the design principles and functions of endogenous pH sensitive proteins regulating actin filament dynamics, cell adhesion, migration and differentiation, dysplasia, and gene expression.
Education and Training
University of Massachusetts Medical Center
Postdoc
Cell Physiology
1987
University of California Los Angeles
PhD
Anatomy
1985
University of California Davis
BS and MS
Physiology
1977
Associated Programs
Publications
Title
Author (s)
Journal
Date Published
Patient-derived induced pluripotent stem cells with a C9orf72 expansion as a model to study frontotemporal dementia pathologies.
Infante-Tadeo S, Barber DL. Patient-derived induced pluripotent stem cells with a C9orf72 expansion as a model to study frontotemporal dementia pathologies. Mol Biol Cell. 2025 Dec 01; 36(12):ar145.
2025-10-08
A role for pH dynamics regulating transcription factor DNA-binding selectivity.
Kisor KP, Ruiz DG, Jacobson MP, Barber DL. A role for pH dynamics regulating transcription factor DNA-binding selectivity. Nucleic Acids Res. 2025 May 22; 53(10).
2025-05-22
Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells.
Meyer NP, Singh T, Kutys ML, Nystul TG, Barber DL. Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells. Elife. 2024 Sep 25; 13.
2024-09-25