The lab of Sarah Knox, PhD, is celebrating the recent publication of its salivary gland research in EMBO Molecular Medicine. “Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement” is in the Jan. 15 edition of the journal.
Co-authors of the paper include Elaine Emmerson, Alison May, Lionel Berthoin, Noel Cruz-Pacheco, Sara Nathan, Aaron Mattingly, Joie Chang, William Ryan and Aaron Tward.
In the abstract, the Knox team posits that salivary glands can regenerate after genotoxic shock (e.g., radiation treatment for head and/or neck cancer).
Other news from the Knox lab includes receipt of a Center for Dental, Oral, Craniofacial Tissue and Organ Regeneration (C-DOCTOR) award for its interdisciplinary translational project, “Promoting salivary gland regeneration using therapeutic delivery of carbachol.” The project was funded in the summer 2017 cycle. C-DOCTOR seeks to recruit interdisciplinary translational project teams from universities and industry nationwide that align with its clinical indication priorities in dental, oral, and craniofacial tissue engineering/regenerative medicine.