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Chelsea Bahney, PhD

Title: Assistant Professor
School: UCSF School of Medicine
Department: Orthopaedic Surgery
Email: Chelsea.Bahney@ucsf.edu
profiles.ucsf.edu/chelsea.bahney

Overview

The overall goal of my research is to develop novel therapies for the treatment of musculoskeletal diseases and injuries. Specifically, I believe we can drive improved tissue regeneration by recapitulating the normal sequences of development and repair. To accomplish this “Developmental Engineering” approach our laboratory utilizes a cross-disciplinary tools combining biologically modified synthetic polymers, stem cell biology, and murine models of orthopaedic injuries. The long-term goal of our research is to solve problems that will have a direct and significant impact on human health.

Current Projects:

  1. Tissue engineering strategies to promote endochondral bone regeneration
  2. Transdifferentiation of cartilage to bone during fracture repair and osteoarthritis
  3. The role of the nerve in fracture repair
  4. Polytraumatic Injuries: How brain trauma influences fracture healing
  5. Impedance sensors to monitor fracture healing

Research Activities and Funding

Bimodal therapeutic application of LIF for regulating chondrogenic fate
UCSF Center for Center for Musculoskeletal Biology and Medicine
July 1, 2017 - July 1, 2018 | Role: PI

Innervation during fracture repair: exploring functional mechanisms and innovative therapeutic repair strategies.
Foundation of Orthopaedic Trauma
Oct. 1, 2015 - Oct. 1, 2017 | Role: PI

Promoting vascularized bone regeneration with endochondral cartilage grafts
AO Foundation Start Up Grant
June 1, 2015 - Jan. 1, 2018| Role: PI

A Murine Model of Polytrauma: Understanding the molecular basis of accelerated bone repair with concomitant traumatic brain injury.
NIH R21
May 1, 2015 - Dec. 31, 2017 | Role: Co-Investigator

OsteoNova: Tissue Engineering Approach to Translating Endochondral Bone Regeneration
UCSF Catalyst
March 1, 2015 - June 30, 2017 | Role: PI

Development of a Novel Impedance Sensor to Monitor Fracture Healing
NSF Center for Disruptive Musculoskeletal Innovation
Aug. 1, 2014 - Aug. 1, 2017 | Role: Co-PI

Tissue engineering application of endochondral ossification for bone regeneration
NIH/NIAMS F32AR062469
March 1, 2012 - Feb. 28, 2015 | Role: Principal Investigator