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Program in Craniofacial Biology

Multidisciplinary scholarship on the craniofacial complex


Ophir Klein, MD, PhD
Program Director

Deepa Saha
Administrative Coordinator


Program in Craniofacial Biology external site
UCSF Craniofacial Center

The UCSF Program in Craniofacial Biology (PCB) brings together faculty, research labs and investigators who are interested in the development and function of the craniofacial complex and of tissues of mesenchymal origin, such as muscle, cartilage and bone. Researchers in the program also study the biology of various stem cells, and how these progenitors differentiate into tissues. Finally, PCB researchers study interactions between tissues, such as those between mesenchymal and epithelial tissues, how tissue differentiation and interactions give rise to normal craniofacial development, and how deregulation of tissue differentiation and interactions is at the basis of many craniofacial anomalies and musculoskeletal diseases.

UCSF Craniofacial Center

The UCSF Craniofacial Center treats all types of conditions affecting the face, head and neck, whether present at birth or acquired from trauma or tumor. The most common conditions include cleft lip, cleft palate and craniosynostosis syndromes, which involve the early fusing of one or more of the bones in the skull and face during fetal development.