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Tejal Desai, PhD

Title: Professor; Chair, Bioengineering and Therapeutic Sciences
School: UCSF School of Pharmacy
Department: Bioengineering
Email: Tejal.Desai@ucsf.edu
profiles.ucsf.edu/tejal.desai

Overview

Dr. Desai’s research brings together advanced micro and nanotechnologies, fundamental insight into cellular behavior in engineered environments, and novel pharmacologic delivery approaches to address disease treatment and clinical translation. Currently, her laboratory focuses on four highly interdisciplinary directions:

  1. Hierarchical devices for enhanced cellular adhesion and paracellular drug transport;
  2. Injectable and flexible nanoporous devices for rate-controlled long term release of therapeutics;
  3. Nanostructured coatings and scaffolds for pro-healing implants and in vivo modulation of fibrosis, and
  4. Cell-based delivery platforms for autoimmune disease applications.

She envisions a future of precision medicine, enabled by advances in nanotechnology, engineering, and cell biology directed to clinical challenges in disease treatment. By taking advantage of our understanding of how cells respond to engineered materials and our ability to fabricate precise structural domains, her lab seeks to design new platforms to overcome existing challenges in therapeutic delivery.

Research Activities and Funding

Mechanisms of nanostructure-enhanced transepithelial drug delivery
NIH/NIBIB R01EB018842
Sept. 18, 2014 - May 31, 2018 | Role: Principal Investigator

Nanoporous Films for Ocular Drug Delivery
NIH/NEI R01EY021574
Sept. 1, 2011 - Aug. 31, 2015 | Role: Principal Investigator

Engineering Particle Nanostructure for Enhanced Bioadhesion
NIH/NIBIB R21EB011664
June 1, 2010 - May 31, 2013 | Role: Principal Investigator

NANOPOROUS INOGANIC BIOCAPSULES
NIH/NIBIB R21EB000570
Sept. 30, 2002 - Feb. 28, 2005 | Role: Principal Investigator

UCSF/UCB Joint Graduate Group in BIoengineering
NIH/NIGMS T32GM008155
July 1, 1985 - June 30, 2021 | Role: Principal Investigator